Indication
x POMALYST® (pomalidomide) is a thalidomide analogue indicated, in combination with dexamethasone, for adult patients with multiple myeloma who have received at least two prior therapies including lenalidomide and a proteasome inhibitor and have demonstrated disease progression on or within 60 days of completion of the last therapy.

See other indications for POMALYST:

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Choosing a POMALYST-
containing regimen

Dr David Siegel summarizes the expansion of POMALYST data across four trials and shares his insights about a POMALYST-containing regimen, including use as early as first relapse, after lenalidomide and a PI.

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DPd is the most prescribed regimen in 2L DPd is the most prescribed regimen in 2L

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Resources and tools for healthcare providers

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Resources and tools for nurses and their patients

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2L, second line; dara SC, daratumumab and hyaluronidase-fihj subcutaneous formulation; dex, dexamethasone; DPd, POMALYST + dexamethasone + daratumumab; HCP, healthcare provider; LoT, lines of therapy; NCCN, National Comprehensive Cancer Network; Pd, POMALYST + dexamethasone; PI, proteasome inhibitor.

References: 1. Referenced with permission from the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) for Multiple Myeloma V.2.2024. © National Comprehensive Cancer Network, Inc. 2023. All rights reserved. Accessed November 10, 2023. To view the most recent and complete version of the guidelines, go online to NCCN.org. NCCN makes no warranties of any kind whatsoever regarding their content, use, or application and disclaims any responsibility for their application or use in any way. 2. POMALYST [package insert]. Summit, NJ: Celgene Corp.3. San Miguel J, Weisel K, Moreau P, et al. Pomalidomide plus low-dose dexamethasone versus high-dose dexamethasone alone for patients with relapsed and refractory multiple myeloma (MM-003): a randomised, open-label, phase 3 trial. Lancet Oncol. 2013;14(11):1055-1066. 4. Daratumumab [package insert]. Horsham, PA: Janssen Biotech, Inc. 5. Daratumumab and hyaluronidase-fihj [package insert]. Horsham, PA: Janssen Biotech, Inc. 6. Bahlis NJ, Siegel D, Schiller G, et al. Pomalidomide, dexamethasone, and daratumumab immediately after lenalidomide-based treatment in patients with multiple myeloma: updated efficacy, safety, and health-related quality of life results from the phase 2 MM-014 trial. Leuk Lymphoma. 2022 Feb 8;1-11. 7. Bristol-Myers Squibb Co; January 2023.